Innovation in diagnostics
Real‑time insight into the body’s processes
Liquid biopsy offers a breakthrough solution for the early detection and dynamic monitoring of cancer. It provides reliable, targeted information without any invasive procedure.
Transformation in oncology
Challenges and solutions in tumor diagnostics
One of the greatest challenges in cancer diagnostics today is obtaining a real-time, accurate picture of the biological processes occurring in the body. These biological changes begin long before they become physically visible.
Traditional
Traditional tissue biopsy is an invasive, painful procedure, and in many cases it provides information only from one region of the tumor. As a result, it may fail to reflect the full genetic diversity of the tumor.
Moreover, a biopsy offers only a single snapshot in time and cannot be repeated indefinitely. Imaging tests are also essential, but they are expensive and often detect abnormalities only once the tumor has reached a certain size and has already caused structural changes in the tissue.
The limitations:
- Invasive and painful procedure
- Captures only a momentary state, cannot be repeated frequently
- Late detection (only when physical changes appear)
“The time gained through early detection can significantly influence treatment decisions and improve survival outcomes.”
Liquid Biopsy
This method is a modern diagnostic technology based on the analysis of free nucleic acids and tumor-derived DNA and RNA fragments extracted from various body fluids (such as saliva, blood, or urine).
Tumors release tiny genetic signals into the circulation even in very early stages. The more active the tumor’s growth, the more of these molecular signals appear. Changes in their quantity and genetic patterns can be monitored in real time.
Tumor Heterogeneity
Because liquid biopsy analyzes tumor-derived genetic signals present in the circulation and in excreted body fluids, it is able to reflect the different biological behaviors of various regions of the tumor.
Dynamic Monitoring
If a treatment is effective, the amount of tumor-derived nucleic acids may decreas over time. With this method, the entire course of the disease can be continuously monitored.
One of the greatest advantages of liquid biopsy is that it is non-invasive or minimally invasive, painless, and can be repeated at any time if needed - which makes a significant difference in patients’ quality of life. Unlike traditional methods that examine only a single tissue fragment, liquid biopsy analyzes genetic signals found in the blood and other excreted body fluids. As a result, it can provide a realistic picture of the tumor’s biological behavior and heterogeneity - meaning the different genetic compositions of various tumor regions. This is clinically essential, as therapeutic decisions are truly effective only when they are based on the actual biological state.
